Hara Y, Morimoto K, Nakamura Y, Sasaki S, Kuroda H, Mori T, Tanaka K, Nishikawa K
Second Department of Surgery, Tottori University Medical School, Japan.
Kyobu Geka. 1993 May;46(5):438-41.
A 61-year-old man underwent aortic valve replacement and received transfusion of 8 units of stored blood. Erythema appeared on the entire body the 12th day after operation, and was followed by high fever, elevation of liver enzymes, progressive pancytopenia, aplastic bone marrow and diarrhea. He died due to septic shock on the 19th postoperative day. Skin biopsy showed the typical features observed in graft-versus-host disease (GVHD). Based on the clinical course, skin and bone marrow biopsy, we diagnosed as post-transfusion GVHD. Therefore, even when stored blood or stored red blood cells are used, these should be irradiated and transfused through the leukocyte removal filter.
一名61岁男性接受了主动脉瓣置换术，并输注了8单位库存血。术后第12天全身出现红斑，随后出现高热、肝酶升高、进行性全血细胞减少、再生障碍性骨髓和腹泻。他在术后第19天因感染性休克死亡。皮肤活检显示出移植物抗宿主病（GVHD）的典型特征。根据临床病程、皮肤和骨髓活检，我们诊断为输血后GVHD。因此，即使使用库存血或库存红细胞，也应进行辐照并通过白细胞滤除器输注。
