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人类免疫缺陷病毒疫苗研发的科学与社会问题。

Scientific and social issues of human immunodeficiency virus vaccine development.

作者信息

Haynes B F

机构信息

Duke University School of Medicine, Durham, NC.

出版信息

Science. 1993 May 28;260(5112):1279-86. doi: 10.1126/science.8493572.

DOI:10.1126/science.8493572
PMID:8493572
Abstract

Development of a preventive immunogen for human immunodeficiency virus (HIV) infection is a national priority. The complexities associated with HIV host-virus interactions, coupled with the rapid progression of the HIV epidemic worldwide, have necessitated lowering expectations for an HIV vaccine that is 100 percent effective and have raised important scientific and nonscientific issues regarding development and use of preventive and therapeutic HIV vaccines.

摘要

研发用于预防人类免疫缺陷病毒（HIV）感染的免疫原是一项国家优先事项。与HIV宿主-病毒相互作用相关的复杂性，再加上全球HIV疫情的迅速蔓延，使得人们不得不降低对百分百有效的HIV疫苗的期望，并引发了有关预防性和治疗性HIV疫苗研发及使用的重要科学和非科学问题。

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