Schomerus H, Schreiegg J
II. Medizinische Klinik, Diakoniekrankenhaus, Rotenburg, Wümme.
Z Gastroenterol. 1993 Apr;31(4):231-4.
To evaluate the prevalence of latent PSE in unselected ambulatory patients with liver cirrhosis practicing physicians were asked to perform two non instrumental psychometric tests (number connection test and line tracing test) on patients with clinical signs of liver cirrhosis and portal hypertension. Tests were repeated after 8 weeks of treatment with Lactulose in those patients considered to have latent PSE at the initial evaluation. 296 physicians tested a total of 783 patients, 771 of these could be evaluated. 551 patients (71.5%) were considered to have latent PSE. There was a significant correlation between psychometric test results and biochemical parameters related to liver function. Repeat testing after 8 weeks treatment with Lactulose revealed definite improvement of psychometric test results in 88% of the patients. At the final evaluation only about 30% of the patients fulfilled the criteria of latent PSE. There was a statistically significant albeit weak correlation between changes in biochemical parameters and psychometric improvement. Psychometric testing with simple non instrumental tests proved to be practicable in the office setting.
为评估非选择性肝硬化门诊患者中潜在肝性脊髓病（PSE）的患病率，要求执业医师对有肝硬化和门静脉高压临床体征的患者进行两项非仪器心理测量测试（数字连接测试和划消试验）。在初始评估中被认为有潜在PSE的患者，在接受乳果糖治疗8周后重复进行测试。296名医师共测试了783例患者，其中771例可进行评估。551例患者（71.5%）被认为有潜在PSE。心理测量测试结果与肝功能相关生化参数之间存在显著相关性。乳果糖治疗8周后重复测试显示，88%的患者心理测量测试结果有明显改善。在最终评估时，只有约30%的患者符合潜在PSE的标准。生化参数变化与心理测量改善之间存在统计学上显著但较弱的相关性。事实证明，在门诊环境中使用简单的非仪器测试进行心理测量测试是可行的。
