Miranda Vallina C, Fernández Seara J, Martínez Alarcón M, Mazorra F, Ondiviela R
Servicio de Anatomía Patológica, Hospital Santa María Madre, Orense.
Rev Esp Enferm Dig. 1993 Apr;83(4):273-5.
Ganglioneuroma is an exceptional benign tumour of the duodenum and only three cases have been described previously. We report the case of a 71-year-old male in whom this pathology was incidentally discovered, as it usually happens with this type of tumour. Within rare duodenal nonepithelial tumours, gangliocytic paraganglioma is a fairly well defined entity characterized by a proliferation of neurons, Schwann cells, and endocrine-like epithelial cells. Ganglioneuroma lacks this last type of cells and represents and even rarer finding within tumoral pathology of the duodenum. The histopathogenesis of this tumor is discussed and there are theories that defend an hamartomatous origin against a neoplastic nature.
神经节瘤是一种罕见的十二指肠良性肿瘤,此前仅有三例相关报道。我们报告一例71岁男性患者,该病例为此种病变偶然发现,此类肿瘤通常如此。在罕见的十二指肠非上皮性肿瘤中,神经节细胞性副神经节瘤是一种定义较为明确的实体,其特征为神经元、施万细胞和内分泌样上皮细胞的增殖。神经节瘤缺乏最后一种细胞类型,在十二指肠肿瘤病理学中更为罕见。本文讨论了该肿瘤的组织病理发生机制,有理论支持其错构瘤起源而非肿瘤性质。