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[在固定电位下通过离子电流分析蛙心房小梁膜的电生理特性]

[Analysis of electrophysiologic characteristics of the frog atrial trabecular membrane by ionic currents at a fixed potential].

作者信息

Pertsov A M, Krinskiĭ V I, Kokoz Iu M, Kuz'minykh S B

出版信息

Biofizika. 1977 Jan-Feb;22(1):102-7.

PMID:849487
Abstract

The membrane of frog auricle trabecula was studied by the method of potential fixation. On the basis of the records of ionic currents zyro-isoclines of approximative differential equations of the 2nd order, describing the membrane studied, were plotted. The mathematical model of this membrane was analysed with the help of qualitative methods of the oscillation theory. The analysis has shown that the following phenomena which have not been observed experimentally should take place in the membrane of frog auricle trabecula: 1. absence of the minimum gradient and accomodation growth of thresholds; 2. absence of anode-disconnecting excitation; 3. coincidence of the current of repeated responses with that of the rheobase; 4. uneven depolarization.

摘要

采用电位固定法对蛙心耳小梁膜进行了研究。根据离子电流记录,绘制了描述所研究膜的二阶近似微分方程的零等斜线。借助振荡理论的定性方法对该膜的数学模型进行了分析。分析表明,蛙心耳小梁膜应会出现以下尚未在实验中观察到的现象:1. 不存在最小梯度且阈值适应性增长;2. 不存在阳极断路兴奋;3. 重复反应电流与基强度电流一致;4. 去极化不均匀。

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