Pertsov A M, Shapovalova L M, Shcheglova E A
Biofizika. 1977 Mar-Apr;22(2):294-9.
Measurements were carried out by the method of double succrose gap. Accommodation was practically absent in all the preparations studied: the minimal gradient was not observed, the mean value of accommodation was 0.02 rheobasa/s, saturation current/H practically coincided with the current of rheobase IO(IH/IO = 1.0 +/- 0.1). Repeated responses were initiated in 1/3 of samples. The current of initiating the repeated responses IRR was insignificantly higher than the rheobase one (IRR/IO = 1.2 +/- 0.1). In the samples where the replated responses were absent the effect of uneven depolarization was observed. At depolarization current which was insignificantly higher than the threshold one (IO), the potential did not return to the resting potential and was settled at the level of -20 mV. Anode disconnecting excitation was absent in all the samples. The hyperpolarization level varied from -90 to -160 mV. The data obtained well agree with the results of the analysis of the mathematical model of frog auricle trabecula membrane constructed on the basis of the data on the potential fixation.
采用双蔗糖间隙法进行测量。在所研究的所有制剂中几乎不存在适应性:未观察到最小梯度,适应性的平均值为0.02 rheobasa/s,饱和电流/H实际上与基强度电流IO一致(IH/IO = 1.0 +/- 0.1)。三分之一的样本引发了重复反应。引发重复反应的电流IRR略高于基强度电流(IRR/IO = 1.2 +/- 0.1)。在未出现重复反应的样本中,观察到了不均匀去极化的效应。在略高于阈值电流(IO)的去极化电流下,电位未恢复到静息电位,而是稳定在-20 mV的水平。所有样本中均未出现阳极断开兴奋。超极化水平在-90至-160 mV之间变化。所获得的数据与基于电位固定数据构建的青蛙心房小梁膜数学模型的分析结果非常吻合。