中国人群中人纤溶酶原（PLG）的基因多态性。

Genetic polymorphism of human plasminogen (PLG) in a Chinese population.

作者信息

Yiping H, Qing G, Meiyun W

机构信息

Department of Forensic Serology, West China University of Medical Sciences, Chengdu.

出版信息

Eur J Immunogenet. 1993 Apr;20(2):91-4. doi: 10.1111/j.1744-313x.1993.tb00097.x.

DOI:10.1111/j.1744-313x.1993.tb00097.x

PMID:8494872

Abstract

The distribution of phenotypes and gene frequencies of the plasminogen were studied in 203 blood donors of the Han population, Chengdu, China using isoelectric focusing followed by immunofixation. The results were as follows: PLGA = 92.12%, PLGAM5 = 4.39%, PLGAB = 1.97%, PLGAB2 = 0.98%. Their gene frequencies were: PLGA = 0.9606, PLGM5 = 0.0246, PLGB = 0.0099, PLGB2 = 0.0049. This study implied that PLG*M5 might be the specific genetic marker of the Mongoloids.

摘要

采用等电聚焦后免疫固定法，对中国成都汉族人群的203名献血者进行纤溶酶原的表型分布和基因频率研究。结果如下：PLGA = 92.12%，PLGAM5 = 4.39%，PLGAB = 1.97%，PLGAB2 = 0.98%。其基因频率为：PLGA = 0.9606，PLGM5 = 0.0246，PLGB = 0.0099，PLGB2 = 0.0049。本研究提示PLG*M5可能是蒙古人种的特异性遗传标记。