Murakami T, Taniguchi Y, Noguchi S, Nakanishi K, Matsuura B, Kitai K, Ohta Y
Third Department of Internal Medicine, Ehime University School of Medicine, Japan.
Intern Med. 1993 Jan;32(1):46-9. doi: 10.2169/internalmedicine.32.46.
A 49-year-old female with a metastatic renal cell carcinoma to the thyroid is presented. The thyroglobulin (Tg) level in tumor aspirates of this patient was 37.3 micrograms/l, while that of 49 patients with primary thyroid nodules ranged from 2.0 x 10(3) to 7.5 x 10(8) micrograms/l. Ultrasonogram of the thyroid demonstrated a well-demarcated oval nodule with a cystic region, the solid part of which was hypoechoic and homogeneous. However, similar ultrasonic findings were observed in only 1.1% of 1,054 patients with primary thyroid nodules. Determination of Tg in tumor aspirates and ultrasonography of the thyroid may contribute to the differentiation of metastatic thyroid nodules from primary thyroid nodules.
本文报告了一名49岁的女性，其甲状腺发生了转移性肾细胞癌。该患者肿瘤抽吸物中的甲状腺球蛋白（Tg）水平为37.3微克/升，而49例原发性甲状腺结节患者的Tg水平范围为2.0×10³至7.5×10⁸微克/升。甲状腺超声检查显示一个边界清晰的椭圆形结节，伴有囊性区域，其实性部分呈低回声且均匀。然而，在1054例原发性甲状腺结节患者中，只有1.1%观察到类似的超声表现。肿瘤抽吸物中Tg的测定以及甲状腺超声检查可能有助于区分转移性甲状腺结节和原发性甲状腺结节。
