Yu H M, Wu T M, Chen S T, Ho C L, Her G R, Wang K T
Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Biochem Mol Biol Int. 1993 Feb;29(2):241-6.
Mastoparan B, a tetradecapeptide toxin (LKLKSIVSWAKKVL) isolated from the hornet (Vespa basalis) venom, was synthesized chemically. The physical and biological properties of both the native and synthetic peptides were studied and proved to be identical. Mastoparan B was found to have a potent antibacterial activity to both Gram negative and Gram positive bacteria.
蜂毒肽B是一种从黄蜂(金环胡蜂)毒液中分离出来的十四肽毒素(LKLKSIVSWAKKVL),已通过化学合成得到。对天然肽和合成肽的物理及生物学特性进行了研究,结果证明二者相同。研究发现蜂毒肽B对革兰氏阴性菌和革兰氏阳性菌均具有强大的抗菌活性。