Matsumoto T, Fukaya Y, Yoshitomi S, Arafuka M, Kubo N, Ohno Y
Department of Public Health, Nagoya City University Medical School, Japan.
Environ Res. 1993 May;61(2):299-307. doi: 10.1006/enrs.1993.1074.
In this study, four experiments using the tapping test were conducted to evaluate the possible subclinical effects of lead exposure on the neuromuscular systems of lead workers at some transfer printing factories in Japan. Decreases in the tapping ability appeared coincidentally with higher blood lead levels. The recovery of the tapping ability after 30 sec rest in the groups of 30-45 micrograms/dl and above 45 micrograms/dl PbB was worse than that in the group with less than 29 micrograms/dl PbB. The recovery of the decreased tapping ability after 60 sec rest was better even in the group with 30-45 micrograms/dl PbB. The tapping ability for 0-10 sec at the first tapping test was sustained after 30 or 60 sec rest in the group with the PbB below 29 micrograms/dl; however, the tapping ability at the second and third tapping test decreased in the two groups with the PbB level above 30 micrograms/dl. The decreased finger tapping speed may be functional evidence of low-grade motor neuropathy among the workers with higher levels of lead absorption.
在本研究中,进行了四项使用敲击测试的实验,以评估铅暴露对日本一些移印工厂铅作业工人神经肌肉系统可能产生的亚临床影响。敲击能力的下降与较高的血铅水平同时出现。血铅水平在30 - 45微克/分升及高于45微克/分升的组中,休息30秒后敲击能力的恢复比血铅水平低于29微克/分升的组更差。即使在血铅水平为30 - 45微克/分升的组中,休息60秒后下降的敲击能力的恢复也更好。在血铅水平低于29微克/分升的组中,第一次敲击测试0 - 10秒的敲击能力在休息30秒或60秒后得以维持;然而,在血铅水平高于30微克/分升的两组中,第二次和第三次敲击测试的敲击能力下降。手指敲击速度的下降可能是铅吸收水平较高的工人中轻度运动神经病变的功能性证据。