Avinoah E, Ben-Yehuda A, Ovnat A, Pilpel D, Charuzi I
Dept. of Surgery C, Soroka Medical Center, Beer Sheba.
Harefuah. 1993 Feb 15;124(4):185-7, 248.
100 patients were followed for 6-9 years after Roux-en-Y gastric bypass for morbid obesity. They were randomly selected from 600 patients operated on between 1980-85. Their initial weight averaged 118 +/- 16 kg, which was 196 +/- 25% of their ideal body weight. They reached their lowest weight during an average of 15.5 months after surgery, at which time 37% were at their ideal weight, 42% were 110-130% of their ideal weight and 21% were 131-192% of their ideal weight. 90% had lost more than 50% of their excess weight. 24% had lost all their excess weight or even more, which could jeopardize nutritional status. Longer follow-up of 6-9 years showed weight gain, with 24% having become morbidly obese again, 74% having lost more than 50% of their excess weight and only 7% having lost all their excess weight. We conclude that Roux-en-Y gastric bypass induces long term weight loss and largely prevents return of morbid obesity, as long as 6-9 years after surgery.
100例病态肥胖患者接受了Roux-en-Y胃旁路手术后随访6至9年。他们是从1980年至1985年间接受手术的600例患者中随机选取的。他们的初始体重平均为118±16千克,是其理想体重的196±25%。他们在术后平均15.5个月时达到最低体重,此时37%的人体重达到理想体重,42%的人体重为理想体重的110 - 130%,21%的人体重为理想体重的131 - 192%。90%的患者减轻了超过50%的超重体重。24%的患者减掉了所有超重体重甚至更多,这可能危及营养状况。6至9年的更长随访期显示体重有所增加,24%的患者再次变得病态肥胖,74%的患者减掉了超过50%的超重体重,只有7%的患者减掉了所有超重体重。我们得出结论,Roux-en-Y胃旁路手术可实现长期体重减轻,并在很大程度上防止病态肥胖复发,术后长达6至9年都是如此。