Rapaport E
Cardiovasc Clin. 1977;8(1):269-77.
Valvular replacement should generally be reserved for patients with valvular heart disease who are symptomatic. With the exception of an occasional case of tight aortic stenosis, morbidity and mortality are less in the asymptomatic patient managed medically versus surgically with prosthetic valve replacement. Therefore, patients with valvular lesions are best managed without prosthetic valve surgery until less than ordinary exertion makes the patient clearly symptomatic. At this point, significant hemodynamic impairment at rest is present, and the prognosis is worse if the patient is managed medically rather than surgically. Until then, however, one should not operate on an asymptomatic or minimally symptomatic patient with valvular heart disease, particularly when the surgical procedure can be expected to require valve replacement.
瓣膜置换术一般应保留给有症状的瓣膜性心脏病患者。除偶尔出现的重度主动脉瓣狭窄病例外,对于无症状患者,药物治疗的发病率和死亡率低于人工瓣膜置换手术治疗。因此,在患者因日常活动减少而出现明显症状之前,瓣膜病变患者最好采用非人工瓣膜手术治疗。此时,患者静息时存在明显的血流动力学损害,若采用药物治疗而非手术治疗,预后会更差。然而,在此之前,不应为无症状或症状轻微的瓣膜性心脏病患者进行手术,尤其是预计手术需要进行瓣膜置换时。