系统性红斑狼疮中的类别特异性抗核抗体。
Class specific antinuclear antibodies in systemic lupus erythematosus.
作者信息
Savitri K, Sehgal S, Datta B N, Chugh K S
机构信息
Department of Immunopathology, Postgraduate Institute of Medical Education & Research, Chandigarh.
出版信息
Indian J Med Res. 1993 Feb;98:27-9.
The incidence and significance of class specific antinuclear antibodies (ANA), specially with relevance to clinical manifestations of arthritis, renal disease and serositis was studied in 40 patients of systemic lupus erythematosus by the indirect immunofluorescent method. Clinical activity was scored by Morimoto's scoring system. A significant correlation was obtained between IgD ANA and clinical activity of the disease and IgG ANA exhibiting lupus pattern of immunofluorescence and serositis.
采用间接免疫荧光法对40例系统性红斑狼疮患者进行研究，以探讨类别特异性抗核抗体（ANA）的发生率及其意义，特别是与关节炎、肾脏疾病和浆膜炎临床表现的相关性。临床活动度采用森本评分系统进行评分。发现IgD ANA与疾病临床活动度以及呈现狼疮免疫荧光模式和浆膜炎的IgG ANA之间存在显著相关性。
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