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湿疹和花粉热中的人类白细胞抗原

HLA in eczema and hay fever.

作者信息

Turner M W, Brostoff T J, Wells R S, Stokes C R, Soothill J F

出版信息

Clin Exp Immunol. 1977 Jan;27(1):43-7.

Abstract

The presumed HLA haplotype A1:B8 was more frequent and the combination of A3 and B7 was less frequent in allergic subjects presenting with eczema, than in those presenting with hayfever. A1:B8 was most frequent (36%) in eczema complicated by asthma and/or hay fever, and least frequent (5%) in hay fever alone, considerably above and below the frequency in the general population (17%).

摘要

与患有花粉症的过敏患者相比,患有湿疹的过敏患者中假定的人类白细胞抗原(HLA)单倍型A1:B8更为常见,而A3和B7的组合则较少见。在合并哮喘和/或花粉症的湿疹患者中,A1:B8最为常见(36%),而仅患有花粉症的患者中最少见(5%),显著高于和低于普通人群中的频率(17%)。

本文引用的文献

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Analysis of HL-A incompatibility in human renal transplants.人类肾移植中HL-A不相容性的分析。
Tissue Antigens. 1971;1(2):57-67. doi: 10.1111/j.1399-0039.1971.tb00079.x.
9
HL-A types in atopic dermatitis.特应性皮炎中的组织相容性抗原-A类型
Lancet. 1973 May 12;1(7811):1059-60. doi: 10.1016/s0140-6736(73)90694-6.
10
H-LA 1 and 8 in childhood coeliac disease.儿童乳糜泻中的H - LA 1和8
Lancet. 1973 Mar 24;1(7804):668. doi: 10.1016/s0140-6736(73)92234-4.

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