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重度哮喘与社会阶层之间的关系。

The relationship between severe asthma and social class.

作者信息

Littlejohns P, Macdonald L D

机构信息

Department of Public Health Sciences, St Georges Hospital Medical School, London, U.K.

出版信息

Respir Med. 1993 Feb;87(2):139-43. doi: 10.1016/0954-6111(93)90142-m.

Abstract

Asthma is one of the few diseases which has been reported to be common in the higher social classes. In order to assess the relationship between severe asthma and social class we analysed a national study of disabled adults undertaken by the Office of Population Censuses and Surveys (OPCS). The study estimated that there were 5.8 million people over 16 years with some degree of disability living in private households in England and Wales. Thirteen percent of disabilities were due to respiratory disease: 6% chronic bronchitis and emphysema, 3% asthma and allergy, and 4% other respiratory diseases. Among 10,000 individuals interviewed, 338 disabled adults reported asthma as a contributing cause of their disability. Of 291 cases with social class recorded, 41 (14%) were in social classes 1 and 2, 128 (44%) in social class 3, and 122 (42%) in social classes 4 and 5. An estimate of the relationship between social class and adult asthma in the general population was derived by calculating a morbidity ratio for the different social classes. The morbidity ratio for all social classes combined equals 100: for social classes 1 and 2 it was 63 (95% confidence intervals 48, 91); 93 (95% confidence intervals 77, 109) for social class 3; and 131 (95% confidence intervals 108, 153) for social classes 4 and 5. Adults in social classes 4 and 5 were approximately twice as likely to have severe asthma as those in social classes 1 and 2. This could be as a result of differences in the prevalence or treatment of asthma among the social classes.

摘要

哮喘是为数不多的据报道在较高社会阶层中较为常见的疾病之一。为了评估重度哮喘与社会阶层之间的关系,我们分析了人口普查与调查办公室(OPCS)开展的一项针对成年残疾人的全国性研究。该研究估计,在英格兰和威尔士,有580万16岁以上的人生活在私人家庭中,且有某种程度的残疾。13%的残疾是由呼吸系统疾病导致的:6%为慢性支气管炎和肺气肿,3%为哮喘和过敏,4%为其他呼吸系统疾病。在接受访谈的10000人中,338名成年残疾人报告哮喘是导致其残疾的一个原因。在记录了社会阶层的291个病例中,41例(14%)属于社会阶层1和2,128例(44%)属于社会阶层3,122例(42%)属于社会阶层4和5。通过计算不同社会阶层的发病率比,得出了普通人群中社会阶层与成年哮喘之间关系的一个估计值。所有社会阶层综合起来的发病率比为100:社会阶层1和2为63(95%置信区间48, 91);社会阶层3为93(95%置信区间77, 109);社会阶层4和5为131(95%置信区间108, 153)。社会阶层4和5的成年人患重度哮喘的可能性大约是社会阶层1和2成年人的两倍。这可能是由于社会阶层之间哮喘患病率或治疗情况存在差异所致。

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