Pirovino M
Medizinische Klinik, Kantonsspital Olten.
Schweiz Med Wochenschr. 1993 May 1;123(17):873-80.
Gastric lavage, intestinal charcoal decontamination and specific drug antagonism, therapeutic measures widely applied in other intoxications, are of no clear benefit or unavailable in patients with alcohol intoxication. The gastric first-pass-effect is important in modifying the kinetics of alcohol, and clinically relevant drug-alcohol interactions occur in situations of both acute and chronic alcohol abuse. Alcohol-induced hypoglycemia and ketoacidosis should be considered in every severely ill alcoholic patient. The recognition of alcoholism is important and rewarding, since therapeutic action by the practicing physician can be of significant help.
洗胃、肠道活性炭解毒以及特定药物拮抗作用，这些在其他中毒情况中广泛应用的治疗措施，对酒精中毒患者并无明显益处或无法实施。胃的首过效应在改变酒精动力学方面很重要，并且在急性和慢性酒精滥用情况下都会发生临床相关的药物 - 酒精相互作用。对于每一位重症酒精中毒患者，都应考虑酒精诱导的低血糖和酮症酸中毒。认识到酒精中毒很重要且有益，因为执业医师的治疗行动可能会有很大帮助。
