Han Y, Vergroesen I, Spaan J A
Department of Medical Physics and Medical Informatics, Faculty of Medicine, University of Amsterdam, The Netherlands.
Am J Physiol. 1993 May;264(5 Pt 2):H1624-8. doi: 10.1152/ajpheart.1993.264.5.H1624.
We measured epicardial lymph pressure (Plymph) in the anesthetized goat (n = 5 goats). To study the transmission of systolic left ventricular pressure (PLV) to Plymph, the effect of an increase in PLV caused by clamping of the descending aorta on Plymph was evaluated. Peak systolic PLV was 131 +/- 4 (+/- SE) mmHg during control (43 beats) and 188 +/- 4 mmHg when elevated due to aortic clamping (157 beats). Peak systolic Plymph was 24.8 +/- 1.0 and 34.8 +/- 1.1 mmHg during control and elevated PLV, respectively. In the first beat of elevated PLV, peak Plymph did not change, although the pressure waveform did. In the subsequent beats, Plymph increased proportionally with increased PLV. When PLV was decreased back to control, Plymph also decreased but did not reach control level until after three beats. The relationship between normalized Plymph and normalized PLV is given by Plymph = 0.70 x PLV + 0.09. The results show that PLV does affect Plymph in a normal beating heart.
我们测量了麻醉山羊（n = 5只山羊）的心外膜淋巴压力（Plymph）。为了研究收缩期左心室压力（PLV）向Plymph的传导，评估了降主动脉夹闭导致PLV升高对Plymph的影响。在对照期间（43次搏动），收缩期PLV峰值为131±4（±SE）mmHg，主动脉夹闭导致PLV升高时为188±4 mmHg（157次搏动）。对照期间和PLV升高时，收缩期Plymph峰值分别为24.8±1.0和34.8±1.1 mmHg。在PLV升高的第一个搏动中，尽管压力波形发生了变化，但Plymph峰值没有改变。在随后的搏动中，Plymph随PLV升高而成比例增加。当PLV降至对照水平时，Plymph也下降，但直到三次搏动后才达到对照水平。标准化Plymph与标准化PLV之间的关系为Plymph = 0.70×PLV + 0.09。结果表明，在正常跳动的心脏中，PLV确实会影响Plymph。
