依托泊苷单药治疗骨朗格汉斯细胞组织细胞增多症后发生急性髓系白血病。
Acute myeloid leukemia after single-agent treatment with etoposide for Langerhans' cell histiocytosis of bone.
作者信息
Haupt R, Comelli A, Rosanda C, Sessarego M, De Bernardi B
机构信息
Department of Hematology-Oncology, G. Gaslini Children's Hospital, Genova, Italy.
出版信息
Am J Pediatr Hematol Oncol. 1993 May;15(2):255-7. doi: 10.1097/00043426-199305000-00015.
Abstract
The first case of secondary leukemia (FAB M3 microgranular variant) after single-agent chemotherapy with etoposide is described. The peculiar morphology and the absence of previously described cytogenetic abnormalities make this case of interest and emphasize the need for further study of epipodophyllotoxin-related leukemia.
摘要
本文描述了首例接受依托泊苷单药化疗后发生的继发性白血病（FAB M3微颗粒变异型）。其独特的形态以及未出现先前描述的细胞遗传学异常，使得该病例具有研究价值，并强调了对表鬼臼毒素相关白血病进行进一步研究的必要性。
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