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悬浮白血病细胞的¹⁹F核磁共振中由体磁化率引起的谱线展宽

Bulk magnetic susceptibility induced broadening in the 19F NMR of suspended leukemic cells.

作者信息

Adebodun F, Post J F

机构信息

Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston 77550.

出版信息

NMR Biomed. 1993 Mar-Apr;6(2):125-9. doi: 10.1002/nbm.1940060204.

DOI:10.1002/nbm.1940060204
PMID:8499242
Abstract

The relevance of bulk magnetic susceptibility (BMS) induced broadening to in vivo NMR studies of intact cells has been examined and the significance of the contribution of BMS difference to the resolution of intra- and extracellular resonances was demonstrated. BMS difference between intra- and extracellular compartments was found to limit the resolution of intra- and extracellular 19F resonances of fluoro compounds in leukemic cells.

摘要

已研究了体磁化率（BMS）诱导展宽与完整细胞体内核磁共振研究的相关性，并证明了BMS差异对细胞内和细胞外共振分辨率贡献的重要性。发现白血病细胞内细胞内和细胞外区室之间的BMS差异限制了氟化合物细胞内和细胞外19F共振的分辨率。

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