Grzelewska-Rzymowska I, Szmidt M, Rozniecki J
Kliniki Pneumonologii i Alergologii Instytutu Medycyny Wewnetrznej AM w Lodzi.
Pneumonol Alergol Pol. 1993;61(1-2):24-8.
In the paper clinical characteristics of patients with aspirin-induced urticaria were performed. The group of 71 patients, 49 women (69%) and 22 men (31%), mean age of sensitivity symptoms demonstration--32.5 years, underwent allergological, laryngological and histamine dihydrochloride inhalatory tests. Nasal polyps were found in 2 persons (2.8%), atopic diseases in 23 persons (32.3%) and at least one feature of atopy in 37 persons (51.9%). 49 subjects (69%) suffered from urticaria which was not associated with ingestion of aspirin. In 22 patients urticaria developed solely due to aspirin. Urticaria not associated with aspirin had been presents for 2 weeks to 30 years before the onset of sensitivity to aspirin. The authors conclude that aspirin-sensitive urticaria results from concomitance of two different phenomena in one person, i.e. sensitivity to aspirin and urticaria not associated with ingestion of the drug.
本文对阿司匹林诱发荨麻疹患者的临床特征进行了研究。该组71例患者中,49例女性(69%),22例男性(31%),出现过敏症状的平均年龄为32.5岁,均接受了变态反应学、喉科学及盐酸组胺吸入试验。发现2例(2.8%)有鼻息肉,23例(32.3%)有特应性疾病,37例(51.9%)至少有一项特应性特征。49例(69%)患者的荨麻疹与阿司匹林摄入无关。22例患者的荨麻疹仅由阿司匹林诱发。与阿司匹林无关的荨麻疹在对阿司匹林敏感症状出现前已存在2周至30年。作者得出结论,阿司匹林敏感性荨麻疹是由于一人同时存在两种不同现象,即对阿司匹林敏感和与药物摄入无关的荨麻疹。