Kresse H, Hausser H, Schönherr E
Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Germany.
Experientia. 1993 May 15;49(5):403-16. doi: 10.1007/BF01923585.
In this review the structure and functions of two non-related proteoglycan families are discussed. One family represents a group of extracellular matrix macromolecules characterized by core proteins with leucine-rich repeat motifs. Within this family special attention is given to those members which carry chondroitin or dermatan sulfate glycosaminoglycan chains. The second family is characterized by repeat sequences of serine and glycine. Their members are products of a single core protein gene and are characteristic constituents of secretory vesicles in cells of the haematopoietic lineage.
在本综述中，讨论了两个不相关的蛋白聚糖家族的结构和功能。一个家族代表一组细胞外基质大分子，其特征是核心蛋白具有富含亮氨酸的重复基序。在这个家族中，特别关注那些带有硫酸软骨素或硫酸皮肤素糖胺聚糖链的成员。第二个家族的特征是丝氨酸和甘氨酸的重复序列。它们的成员是单个核心蛋白基因的产物，是造血谱系细胞中分泌小泡的特征性成分。
