Garner W L, Zuccaro C, Marcelo C, Rodriguez J L, Smith D J
University of Michigan Medical Center, Ann Arbor 48109-0033.
J Burn Care Rehabil. 1993 Mar-Apr;14(2 Pt 1):127-31. doi: 10.1097/00004630-199303000-00001.
The optimal clinical care of burn blisters has not been determined. The effects of burn blister fluid and control serum on epidermal cell proliferation and differentiation were determined. Both burn blister fluid and serum decreased the cell responses necessary for healing of the burn wound by approximately 40%. The degree of suppression varied from 81% to 28% dependency on the specific burn blister fluid and cell tested. These data suggest that reepithelialization may be inhibited beneath burn blisters. We conclude that in most cases burn blisters should be debrided.
烧伤水疱的最佳临床护理方法尚未确定。研究了烧伤水疱液和对照血清对表皮细胞增殖和分化的影响。烧伤水疱液和血清均使烧伤创面愈合所需的细胞反应降低了约40%。抑制程度因所测试的特定烧伤水疱液和细胞而异，从81%到28%不等。这些数据表明，烧伤水疱下方的再上皮化可能受到抑制。我们得出结论，在大多数情况下，烧伤水疱应予以清创。
