Groenewegen A A, Sukhai R N, Nauta J, Scholtmeyer R J, Nijman R J
Department of Pediatric Urology, Sophia Children's Hospital, Erasmus University of Rotterdam, The Netherlands.
J Urol. 1993 Jun;149(6):1517-20. doi: 10.1016/s0022-5347(17)36432-7.
The results of renal transplantation in boys treated for posterior urethral valves were evaluated and compared with a matched control group. Patient and graft survival was equal in both groups, although serum creatinine levels were slightly higher in the posterior urethral valves group. Postoperative complications, such as urinary tract infections, occurred more frequently in the posterior urethral valves group. Urodynamic evaluation was performed before transplantation in 11 of 20 patients. Adequate treatment of bladder dysfunction, such as poor compliance and/or hyperreflexia, is essential in diminishing the risks of secondary graft damage due to severe bladder dysfunction.
对接受后尿道瓣膜治疗的男孩进行肾移植的结果进行了评估，并与匹配的对照组进行了比较。两组的患者和移植物存活率相同，尽管后尿道瓣膜组的血清肌酐水平略高。后尿道瓣膜组术后并发症（如尿路感染）的发生频率更高。20例患者中有11例在移植前进行了尿动力学评估。充分治疗膀胱功能障碍（如顺应性差和/或反射亢进）对于降低因严重膀胱功能障碍导致继发性移植物损伤的风险至关重要。
