Klaasen H L, Koopman J P, Van den Brink M E, Bakker M H, Poelma F G, Beynen A C
Central Animal Laboratory, Catholic University of Nijmegen, The Netherlands.
Lab Anim. 1993 Apr;27(2):141-50. doi: 10.1258/002367793780810441.
Segmented, filamentous bacteria (SFBs) form a group of bacteria with similar morphology and are identified on the basis of their morphology only. The relationships of these organisms are unclear as the application of formal taxonomic criteria is impossible currently due to the lack of an in vitro technique to culture SFBs. The intestine of laboratory animals such as mice, rats, chickens, dogs, cats and pigs is known to harbour SFBs. To see whether this extends to other animal species, intestines from 18 vertebrate species, including man, were examined. SFBs were detected with light microscopy in the cat, dog, rhesus monkey, crab-eating macaque, domestic fowl, South African claw-footed toad, carp, man, laboratory mouse and rat, wood mouse, jackdaw and magpie. These results suggest that non-pathogenic SFBs are ubiquitous in the animal kingdom. Among apparently identical animals, there was considerable variation in the degree of SFB colonization. It is suggested that SFB colonization could serve as a criterion of standardization of laboratory animals.
分段丝状菌（SFBs）构成了一组形态相似的细菌，目前仅根据其形态进行鉴定。由于缺乏体外培养SFBs的技术，目前无法应用正式的分类标准，因此这些微生物之间的关系尚不清楚。已知小鼠、大鼠、鸡、狗、猫和猪等实验动物的肠道中存在SFBs。为了探究这一现象是否也适用于其他动物物种，研究人员检查了包括人类在内的18种脊椎动物的肠道。通过光学显微镜在猫、狗、恒河猴、食蟹猕猴、家禽、南非爪蟾、鲤鱼、人类、实验小鼠和大鼠、林姬鼠、寒鸦和喜鹊中检测到了SFBs。这些结果表明，非致病性SFBs在动物界广泛存在。在看似相同的动物中，SFBs的定殖程度存在相当大的差异。有人认为，SFBs定殖可作为实验动物标准化的一个标准。
