Sung K L, Bradley E L, Terman C R
J Reprod Fertil. 1977 Mar;49(2):201-6. doi: 10.1530/jrf.0.0490201.
Serum corticosterone concentrations were measured to see if there was any correlation between adrenal activity and reproductive inhibition. Males and females from two growing and one stable (asymptotic) population had significantly smaller reproductive organs (seminal vesicles, testes, uteri, ovaries) than controls. The weights of the adrenal glands of population mice were smaller, often significantly so, than those of controls, but the mean serum corticosterone concentrations were higher than those of control mice for the two growing populations and significantly higher for the asymptotic population. These data suggest that adrenal function may be associated with the reproductively inhibited condition, but not in a direct or dose-response fashion and that adrenal hyperfunction in this species may not be reflected by adrenal hypertrophy.
测量血清皮质酮浓度,以观察肾上腺活动与生殖抑制之间是否存在任何相关性。来自两个增长型种群和一个稳定(渐近)种群的雄性和雌性的生殖器官(精囊、睾丸、子宫、卵巢)明显小于对照组。种群小鼠的肾上腺重量小于对照组,通常差异显著,但两个增长型种群的平均血清皮质酮浓度高于对照小鼠,渐近种群的平均血清皮质酮浓度显著更高。这些数据表明,肾上腺功能可能与生殖抑制状态有关,但并非以直接或剂量反应的方式,并且该物种的肾上腺功能亢进可能不会通过肾上腺肥大反映出来。