迟发性压力性荨麻疹患者白细胞介素6升高，但白细胞介素1降低。

Increased interleukin 6, but reduced interleukin 1, in delayed pressure urticaria.

作者信息

Lawlor F, Bird C, Camp R D, Barlow R, Barr R M, Kobza-Black A, Judge M R, Greaves M W

机构信息

St John's Institute of Dermatology, St Thomas' Hospital, London, U.K.

出版信息

Br J Dermatol. 1993 May;128(5):500-3. doi: 10.1111/j.1365-2133.1993.tb00225.x.

DOI:10.1111/j.1365-2133.1993.tb00225.x

PMID:8504039

Abstract

Interleukin 1 (IL-1) and interleukin 6 (IL-6) were measured by bioassays in suction-blister exudates from lesional skin, from skin immediately following a pressure challenge, and from control skin (not subjected to pressure) of patients with delayed pressure urticaria. IL-6 activity in lesional exudates was significantly higher than in exudates from the other two sites. IL-1 activity in lesional exudates was not significantly higher than in the control exudates, but significantly less IL-1 activity was found immediately after pressure challenge than from the control site.

摘要

通过生物测定法测量了迟发性压力性荨麻疹患者皮损皮肤、压力刺激后即刻皮肤以及对照皮肤（未施加压力）的吸疱渗出液中的白细胞介素1（IL-1）和白细胞介素6（IL-6）。皮损渗出液中的IL-6活性显著高于其他两个部位的渗出液。皮损渗出液中的IL-1活性并不显著高于对照渗出液，但压力刺激后即刻发现的IL-1活性明显低于对照部位。