Soft-tissue myxomas and fibrous dysplasia of bone. A case report and review of the literature.

An association between fibrous dysplasia and myxomas (soft-tissue neoplasms of mesenchymal origin) has been described in the literature. The authors report another such case of fibrous dysplasia/myxoma coexistence: a patient with polyostotic fibrous dysplasia who developed right anterior thigh pain from a solitary intramuscular myxoma. After a thorough review of the literature, the authors found that a causal relationship between fibrous dysplasia and myxomata remains uncertain. To ensure an adequate and accurate diagnosis, however, patients with soft-tissue myxomas should be thoroughly evaluated for fibrous dysplasia. A proper investigation of soft-tissue masses also should be carried out to exclude malignancy.