Banta J V, Bonanni C, Prebluda J
Department of Orthopaedic Surgery, Newington Children's Hospital, CT 06111.
Dev Med Child Neurol. 1993 Jun;35(6):543-8. doi: 10.1111/j.1469-8749.1993.tb11686.x.
Intra-operative anaphylaxis to latex involves cutaneous, respiratory and circulatory changes which may prove fatal if not promptly recognized and treated. It is estimated that 18 to 40 per cent of children with spina bifida may be affected by latex allergy. Current tests available lack sufficient sensitivity and specificity to be recommended as routine screening measures, therefore any allergic history in children with myelomeningocele should alert the clinician to the possibility that severe anaphylactic reactions may occur, especially when large mucosal and pleural-peritoneal surfaces are exposed, as noted in the four reported cases. Epinephrine is the drug of choice should a Type 1 reaction occur.
术中对乳胶过敏会引发皮肤、呼吸和循环系统的变化，如果不能及时识别和治疗，可能会致命。据估计，18%至40%的脊柱裂儿童可能会受到乳胶过敏的影响。目前可用的检测方法缺乏足够的敏感性和特异性，因此不建议作为常规筛查措施，所以，脊髓脊膜膨出患儿的任何过敏史都应提醒临床医生，可能会发生严重过敏反应，特别是当大面积黏膜和胸膜-腹膜表面暴露时，如所报道的4例病例所示。如果发生I型反应，肾上腺素是首选药物。
