Czernobilsky B, Zeituni M, Lancet M, Mazor B, Baram A, Deligdish L
Obstet Gynecol. 1977 May;49(5):587-91.
The prevalence of cervicitis, reserve cell hyperplasia, squamous metaplasia, and dysplasia was studied in Jewish women and compared to that reported elsewhere in non-Jewish populations. The study was based on a histologic review of 250 women whose cervices were clinically either normal or presented with minor changes, and of 50 cases of squamous cell carcinoma. The findings indicate that the prevalence of the above-mentioned histologic features in the 2 groups of Jewish women is similar to that observed in comparable groups of non-Jews. It thus appears that in a majority of Jewish women the histologic spectrum leading to cervical cancer unexplicably stops at the dysplastic stage. On the other hand, the results of this study may possibly cast doubt on the well-documented evidence establishing dysplasia as a pre-cancerous lesion. For further elucidation of these problems cytologic studies in matched Jewish and non-Jewish populations will be carried out.
对犹太女性宫颈炎、储备细胞增生、鳞状化生和发育异常的患病率进行了研究,并与其他非犹太人群的报告患病率进行了比较。该研究基于对250名宫颈临床正常或有轻微变化的女性以及50例鳞状细胞癌病例的组织学检查。研究结果表明,两组犹太女性中上述组织学特征的患病率与非犹太对照人群中观察到的患病率相似。因此,在大多数犹太女性中,导致宫颈癌的组织学谱不明原因地停留在发育异常阶段。另一方面,本研究结果可能会对将发育异常确定为癌前病变的充分记录的证据提出质疑。为了进一步阐明这些问题,将在匹配的犹太和非犹太人群中进行细胞学研究。