用于检测和测量抗体 - 抗原亲和力及动力学的表面等离子体共振技术。
Surface plasmon resonance for detection and measurement of antibody-antigen affinity and kinetics.
作者信息
Malmqvist M
机构信息
Pharmacia Biosensor AB, Uppsala, Sweden.
出版信息
Curr Opin Immunol. 1993 Apr;5(2):282-6. doi: 10.1016/0952-7915(93)90019-o.
PMID:8507407
Abstract
Kinetic and affinity information on biospecific interaction can be generated by analysis of adsorption of analyte to immobilized ligand on a sensor based analytical system. The analysis can be performed free of label and directly using culture supernatants. It was found to be particularly valuable for analysis of antibody-antigen interactions.
摘要
通过分析分析物在基于传感器的分析系统中与固定化配体的吸附情况，可以获得生物特异性相互作用的动力学和亲和力信息。该分析无需标记，可直接使用培养上清液进行。结果发现，它在分析抗体-抗原相互作用方面特别有价值。
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