Malmqvist M
Pharmacia Biosensor AB, Uppsala, Sweden.
Nature. 1993 Jan 14;361(6408):186-7. doi: 10.1038/361186a0.
Fundamental information that enhances our understanding of biospecific interactions can be obtained using a new analytical system based on biosensor technology. The functional characteristics of biospecific interaction, such as kinetics, affinity and binding position, are examined by label-free analysis of proteins in free solution binding to an immobilized ligand at a hydrophilic sensor surface.
利用基于生物传感器技术的新型分析系统,可以获得增强我们对生物特异性相互作用理解的基础信息。生物特异性相互作用的功能特性,如动力学、亲和力和结合位置,通过在亲水性传感器表面对游离溶液中与固定配体结合的蛋白质进行无标记分析来检测。