Bohlin L
Department of Pharmacognosy, Uppsala University, Sweden.
J Ethnopharmacol. 1993 Mar;38(2-3):225-31. doi: 10.1016/0378-8741(93)90019-2.
Since 1954, research at the Department of Pharmacognosy at Uppsala University has been oriented towards modern natural products chemistry with emphasis on pharmacologically active compounds. Studies of plants used in the traditional medicine of different cultures have been of major interest. The research strategy is based on: inventory and identification of the plants used, demonstration of pharmacological activity of an extract of the plant, bioassay-guided fractionation, isolation and characterisation of the active compounds and studies of structure activity relationships. Plants from Africa, Asia, The Americas, The Pacific and Europe have been collected in collaboration with botanists and ethnobotanists. Investigations of these plants have resulted in the isolation, and chemical and pharmacological characterization of many different types of compounds. At present the work is focused on compounds with anti-inflammatory and immunomodulatory effects.
自1954年以来，乌普萨拉大学生药学系的研究一直以现代天然产物化学为导向，重点关注具有药理活性的化合物。对不同文化传统医学中使用的植物的研究一直是主要兴趣所在。研究策略基于：对所使用植物的清查和鉴定、植物提取物药理活性的证明、生物测定指导下的分级分离、活性化合物的分离和表征以及构效关系研究。已与植物学家和民族植物学家合作，收集了来自非洲、亚洲、美洲、太平洋地区和欧洲的植物。对这些植物的研究已导致许多不同类型化合物的分离以及化学和药理特性的确定。目前，工作重点是具有抗炎和免疫调节作用的化合物。
