神经垂体肽与精神疾病

Neurohypophyseal peptides and psychiatric diseases.

作者信息

Legros J J, Ansseau M, Timsit-Berthier M

机构信息

Psychoneuroendocrine Unit, University of Liege-Sart Tilman, Belgium.

出版信息

Regul Pept. 1993 Apr 29;45(1-2):133-8. doi: 10.1016/0167-0115(93)90195-e.

DOI:10.1016/0167-0115(93)90195-e

PMID:8511335

Abstract

The study of neurohypophyseal function in various neuropsychiatric diseases is interesting because: (1) The main neurohypophyseal peptides vasopressin (AVP) and oxytocin (OT) share by themselves modulatory influence on behavior. (2) Hypothalamo-posterior pituitary axis is directly influenced by modifications of central neurotransmitter metabolism involved in behavior control.

摘要

对各种神经精神疾病中神经垂体功能的研究很有趣，原因如下：（1）神经垂体的主要肽类物质抗利尿激素（AVP）和催产素（OT）本身对行为具有调节作用。（2）下丘脑 - 垂体后叶轴直接受到参与行为控制的中枢神经递质代谢变化的影响。