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急性白血病患者复发性波氏假阿利什霉鼻窦炎

Recurrent Pseudallescheria boydii sinusitis in acute leukemia.

作者信息

Grigg A P, Phillips P, Durham S, Shepherd J D

机构信息

Leukemia/Bone Marrow Transplantation Program of British Columbia, Vancouver General Hospital, Canada.

出版信息

Scand J Infect Dis. 1993;25(2):263-7. doi: 10.3109/00365549309008495.

DOI:10.3109/00365549309008495
PMID:8511522
Abstract

Most episodes of fungal sinusitis in immunocompromised patients are caused by Aspergillus species. To treat such infections, surgical debridement and anti-fungal therapy have been recommended; it is also clear however that an adequate neutrophil count is important in controlling such infections. We report a case in which fungal sinusitis was shown to be due to P. boydii and in which the infection recurred over a period of 2 years during episodes of neutropenia in spite of vigorous surgical and medical therapy.

摘要

免疫功能低下患者的大多数真菌性鼻窦炎病例是由曲霉菌种引起的。对于治疗此类感染,已推荐采用手术清创和抗真菌治疗;然而,同样明确的是,足够的中性粒细胞计数对于控制此类感染很重要。我们报告一例真菌性鼻窦炎病例,该病例显示由波氏假阿利什霉引起,尽管进行了积极的手术和药物治疗,但在中性粒细胞减少发作期间,感染在2年的时间里反复发作。

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Recurrent Pseudallescheria boydii sinusitis in acute leukemia.急性白血病患者复发性波氏假阿利什霉鼻窦炎
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Case Rep Infect Dis. 2013;2013:589490. doi: 10.1155/2013/589490. Epub 2013 Apr 29.
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Infections caused by Scedosporium spp.由瓶霉属真菌引起的感染
Clin Microbiol Rev. 2008 Jan;21(1):157-97. doi: 10.1128/CMR.00039-07.
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Molecular epidemiology of Scedosporium apiospermum infection determined by PCR amplification of ribosomal intergenic spacer sequences in patients with chronic lung disease.
通过对慢性肺病患者核糖体基因间隔序列进行PCR扩增来确定阿氏丝孢霉感染的分子流行病学
J Clin Microbiol. 2001 Jan;39(1):47-50. doi: 10.1128/JCM.39.1.47-50.2001.
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Scedosporium apiospermum pneumonia after autologous bone marrow transplantation.
Eur J Clin Microbiol Infect Dis. 1996 Jul;15(7):600-3. doi: 10.1007/BF01709371.