Belcher J D, Ellison R C, Shepard W E, Bigelow C, Webber L S, Wilmore J H, Parcel G S, Zucker D M, Luepker R V
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454-1015.
Prev Med. 1993 Mar;22(2):143-53. doi: 10.1006/pmed.1993.1012.
The Child and Adolescent Trial for Cardiovascular Health is a school-based study designed to test the effectiveness of dietary, physical activity, and educational interventions for reducing cardiovascular disease risk and teaching healthful behaviors to children.
As part of a pilot phase in 1989, lipid, lipoprotein, and anthropometric measures were taken in black (n = 90), Hispanic (n = 68), and white (n = 265) 8- to 10-year-old schoolchildren in California, Louisiana, Minnesota, and Texas.
There were no significant differences in mean lipoprotein cholesterol values between fasting and nonfasting children. Therefore data from fasting and nonfasting children were pooled. Males and females within the same ethnic groups had similar mean levels of total cholesterol, low-density lipoprotein cholesterol, and very low-density lipoprotein cholesterol. However, levels of high-density lipoprotein cholesterol were higher among white and black males than among females from the same ethnic groups. Black males had higher total cholesterol than white males and higher high-density lipoprotein cholesterol than white males and Hispanic males. Similarly, black females had higher high-density lipoprotein cholesterol than white and Hispanic females. In all children combined high-density lipoprotein cholesterol was inversely correlated and low-density lipoprotein cholesterol was positively correlated with subscapular and tricep skinfold thickness, weight, and body mass index. There were significant differences in mean lipoprotein cholesterol levels between geographic sites. Total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol were highest in children from California followed by children from Texas, Minnesota, and Louisiana.
Our results suggest that body fatness total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol differ in children by gender, ethnicity, and geographic location.
儿童和青少年心血管健康试验是一项基于学校的研究，旨在测试饮食、体育活动和教育干预措施在降低心血管疾病风险以及向儿童传授健康行为方面的有效性。
作为1989年试点阶段的一部分，对加利福尼亚州、路易斯安那州、明尼苏达州和得克萨斯州8至10岁的黑人（n = 90）、西班牙裔（n = 68）和白人（n = 265）学童进行了血脂、脂蛋白和人体测量。
空腹和非空腹儿童的平均脂蛋白胆固醇值无显著差异。因此，将空腹和非空腹儿童的数据合并。同一族裔群体中的男性和女性总胆固醇、低密度脂蛋白胆固醇和极低密度脂蛋白胆固醇的平均水平相似。然而，白人男性和黑人男性的高密度脂蛋白胆固醇水平高于同种族的女性。黑人男性的总胆固醇高于白人男性，高密度脂蛋白胆固醇高于白人男性和西班牙裔男性。同样，黑人女性的高密度脂蛋白胆固醇高于白人和西班牙裔女性。在所有儿童中，高密度脂蛋白胆固醇与肩胛下和三头肌皮褶厚度、体重和体重指数呈负相关，低密度脂蛋白胆固醇与它们呈正相关。不同地理位置的儿童平均脂蛋白胆固醇水平存在显著差异。总胆固醇、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇在加利福尼亚州的儿童中最高，其次是得克萨斯州、明尼苏达州和路易斯安那州的儿童。
我们的结果表明，儿童的体脂、总胆固醇、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇在性别、种族和地理位置上存在差异。
