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西班牙裔、白人和黑人儿童的心血管危险因素:布鲁克斯县和博加卢萨心脏研究

Cardiovascular risk factors in Hispanic, white, and black children: the Brooks County and Bogalusa Heart studies.

作者信息

Webber L S, Harsha D W, Phillips G T, Srinivasan S R, Simpson J W, Berenson G S

机构信息

Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans 70112-2822.

出版信息

Am J Epidemiol. 1991 Apr 1;133(7):704-14. doi: 10.1093/oxfordjournals.aje.a115945.

DOI:10.1093/oxfordjournals.aje.a115945
PMID:2018025
Abstract

Cardiovascular disease risk factors were studied in Hispanic children in Brooks County, Texas, and in white and black children in Bogalusa, Louisiana, in 1984-1985. The same protocols were used at both sites; examiners in Brooks County were trained by Bogalusa Heart Study staff. All blood samples were analyzed in a single laboratory standardized by the Centers for Disease Control. Hispanic children were about 4 cm shorter and were about the same weight as white and black children. Subscapular skinfolds were thickest in Hispanic children. Little difference was noted for blood pressure levels in the three ethnic groups. Total cholesterol levels were highest in black children, with a drop during puberty being noted in all of the ethnic groups. This drop with puberty appeared somewhat earlier in the Hispanic children. Lipoprotein levels for Hispanic children were, in general, similar to those noted for white children. Some of the Hispanic-black differences in lipid and lipoprotein levels could be explained by differences in body size. Because Hispanics are at increased risk for specific diseases, such as diabetes, increased study of this population is warranted. Intervention and education programs aimed at altering this risk must address the unique cultural heritage of this population.

摘要

1984 - 1985年,在得克萨斯州布鲁克斯县的西班牙裔儿童以及路易斯安那州博加卢萨的白人和黑人儿童中对心血管疾病风险因素进行了研究。两个地点采用相同的方案;布鲁克斯县的检查人员由博加卢萨心脏研究工作人员培训。所有血样均在疾病控制中心标准化的单一实验室进行分析。西班牙裔儿童比白人和黑人儿童矮约4厘米,体重大致相同。西班牙裔儿童的肩胛下皮褶最厚。三个种族群体的血压水平差异不大。黑人儿童的总胆固醇水平最高,所有种族群体在青春期都出现下降。西班牙裔儿童青春期的这种下降出现得稍早一些。西班牙裔儿童的脂蛋白水平总体上与白人儿童相似。西班牙裔和黑人在脂质和脂蛋白水平上的一些差异可以用体型差异来解释。由于西班牙裔患特定疾病(如糖尿病)的风险增加,因此有必要对这一人群进行更多研究。旨在改变这种风险的干预和教育计划必须考虑到这一人群独特的文化遗产。

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