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深静脉血栓形成:高凝状态下硬化疗法的风险。

Deep vein thrombosis: the risks of sclerotherapy in hypercoagulable states.

作者信息

Feied C F

机构信息

Department of Emergency Medicine, George Washington University Medical Center, Washington, DC 20037.

出版信息

Semin Dermatol. 1993 Jun;12(2):135-49.

PMID:8512794
Abstract

There have been many case reports of deep vein thrombosis and pulmonary thromboembolism in patients undergoing sclerotherapy for the treatment of varicose veins, but the true incidence of venous thromboembolism in this patient population is unknown. Patients who develop deep vein thrombosis while being treated for varicose veins do so either because of an error in treatment or because the patient suffers from some underlying hypercoagulable state. It is possible to identify prospectively many patients who are at especially high risk for venous thromboembolism by virtue of genetic predisposition, past or recent medical problems, or environmental factors. When sclerotherapy is used in such patients, special efforts must be made to protect against the development of venous thrombosis during treatment.

摘要

已有许多关于接受硬化疗法治疗静脉曲张的患者发生深静脉血栓形成和肺血栓栓塞的病例报告,但该患者群体中静脉血栓栓塞的真实发生率尚不清楚。在接受静脉曲张治疗时发生深静脉血栓形成的患者,其发生原因要么是治疗失误,要么是患者存在某种潜在的高凝状态。凭借遗传易感性、既往或近期的医疗问题或环境因素,有可能前瞻性地识别出许多静脉血栓栓塞风险特别高的患者。当对这类患者使用硬化疗法时,治疗期间必须特别努力预防静脉血栓形成。

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引用本文的文献

1
[Sclerotherapy for varicosities].[静脉曲张的硬化疗法]
Hautarzt. 2006 Jan;57(1):19-20, 22-5. doi: 10.1007/s00105-005-1072-9.
2
A guide to venous thromboembolism risk factor assessment.静脉血栓栓塞风险因素评估指南
J Thromb Thrombolysis. 2000 Apr;9(3):253-62. doi: 10.1023/a:1018770712660.
3
Sclerotherapy for varicose veins of the lower legs in patients with dysplasminogenemia.低纤溶酶原血症患者小腿静脉曲张的硬化疗法
Surg Today. 1997;27(8):714-8. doi: 10.1007/BF02384983.
4
The possible risk of lower-limb sclerotherapy causing an extended hypercoagulable state.
Surg Today. 1996;26(5):323-7. doi: 10.1007/BF00311600.