Herrmann M, Wallesch C W
Department of Rehabilitation Psychology, Research Program in Neuropsychology and Neurolinguistics, Freiburg, Germany.
Disabil Rehabil. 1993 Apr-Jun;15(2):55-66. doi: 10.3109/09638289309165873.
The present state of research concerning depressive alterations following cerebrovascular infarcts is reviewed with special consideration of methodological issues, the course of depressive changes and interactions with neuropsychological and clinical parameters. The concepts of 'grief response', '(depressive)-catastrophic reactions' and 'post-stroke depression' are analysed and compared. An attempt is made at a theory of post-stroke depressive alterations that is based on neuroanatomical, pathophysiological and neurochemical models of depression and psychosocial changes and interactions. Therapeutic implications are discussed.
本文回顾了脑血管梗塞后抑郁性改变的研究现状，特别考虑了方法学问题、抑郁变化的过程以及与神经心理学和临床参数的相互作用。分析并比较了“悲伤反应”、“（抑郁性）灾难性反应”和“中风后抑郁”的概念。试图基于抑郁症的神经解剖学、病理生理学和神经化学模型以及社会心理变化和相互作用，建立一种中风后抑郁性改变的理论。并讨论了其治疗意义。
