Kuipers H, Peeze Binkhorst F M, Hartgens F, Wijnen J A, Keizer H A
Dept. of Physiology, University of Limburg, Maastricht, The Netherlands.
Can J Appl Physiol. 1993 Jun;18(2):189-96. doi: 10.1139/h93-015.
The influence of strength training on muscle fiber area, capillary ultrastructure, and capillary supply was studied in experienced male bodybuilders taking either anabolic steroids or a placebo. During 8 weeks, 13 subjects received a weekly injection of either placebo or nandrolone decanoate (starting dose 200 mg, followed by 100 mg weekly), in a double-blind, counterbalanced design. Before and after 8 weeks a needle biopsy was taken from the vastus lateralis muscle for studying morphometric characteristics of fibers and ultrastructure and morphometric characteristics of capillaries. The fiber cross-sectional area increased significantly only after steroid treatment. Capillary ultrastructure and capillary supply were not changed after the training period. In none of the measured parameters was any difference found between placebo and steroid treatment.
在服用合成代谢类固醇或安慰剂的有经验的男性健美运动员中，研究了力量训练对肌纤维面积、毛细血管超微结构和毛细血管供应的影响。在为期8周的时间里，13名受试者以双盲、平衡设计，每周接受一次安慰剂或癸酸诺龙注射（起始剂量200毫克，随后每周100毫克）。在8周前后，从股外侧肌进行针吸活检，以研究纤维的形态计量学特征、超微结构以及毛细血管的形态计量学特征。仅在类固醇治疗后，纤维横截面积显著增加。训练期后，毛细血管超微结构和毛细血管供应没有变化。在任何测量参数中，安慰剂和类固醇治疗之间均未发现差异。
