苯丙酸诺龙对马的影响：(1) 静息动物。

Effects of nandrolone phenylpropionate in the horse: (1) resting animal.

作者信息

Snow D H, Munro C D, Nimmo M A

出版信息

Equine Vet J. 1982 Jul;14(3):219-23. doi: 10.1111/j.2042-3306.1982.tb02398.x.

DOI:10.1111/j.2042-3306.1982.tb02398.x

Abstract

The effects of 7 weekly injections of the anabolic steroid nandrolone phenylpropionate (400 mg) were investigated in 4 healthy, mature geldings. Measurement of body weight, nitrogen retention and plasma urea failed to demonstrate a consistent anabolic effects. Examination of biopsies from the semitendinosus and biceps femoris muscles showed no alteration in water content or glycogen concentration with treatment. Similarly no changes were found in the activities of 6 muscle enzymes. However, a significant increase in the proportion of fast twitch low oxidative fibres of the biceps femoris was observed. The effects of the treatment on a wide range of plasma biochemical constituents were investigated. The occurrence of some components of stallion behaviour in the geldings was taken to reflect a residual androgenic activity in the compound.

摘要

研究了每周给4匹健康、成熟的去势雄马注射7次合成代谢类固醇苯丙酸诺龙（400毫克）的效果。对体重、氮潴留和血浆尿素的测量未能显示出一致的合成代谢作用。对来自半腱肌和股二头肌的活检组织进行检查，结果显示治疗后肌肉的含水量或糖原浓度没有变化。同样，6种肌肉酶的活性也没有发现变化。然而，观察到股二头肌中快肌低氧化纤维的比例显著增加。研究了该治疗对多种血浆生化成分的影响。去势雄马出现种马行为的某些成分被认为反映了该化合物中残留的雄激素活性。