• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

作者信息

Jarrett J T, Lansbury P T

机构信息

Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139.

出版信息

Cell. 1993 Jun 18;73(6):1055-8. doi: 10.1016/0092-8674(93)90635-4.

DOI:10.1016/0092-8674(93)90635-4
PMID:8513491
Abstract
摘要

相似文献

1
Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?引发淀粉样蛋白的“一维结晶”：阿尔茨海默病和羊瘙痒病的一种致病机制？
Cell. 1993 Jun 18;73(6):1055-8. doi: 10.1016/0092-8674(93)90635-4.
2
The role of perivascular and microglial cells in fibrillogenesis of beta-amyloid and PrP protein in Alzheimer's disease and scrapie.
Res Immunol. 1992 Jul-Aug;143(6):642-5. doi: 10.1016/0923-2494(92)80049-q.
3
Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins.
Annu Rev Biochem. 1997;66:385-407. doi: 10.1146/annurev.biochem.66.1.385.
4
Amyloid, amyloid-inducers, cytokines and heavy metals in scrapie and other human and animal subacute spongiform encephalopathies: some hypotheses.
Med Hypotheses. 1993 Feb;40(2):113-6. doi: 10.1016/0306-9877(93)90139-h.
5
Ultrastructural links between scrapie and Alzheimer's disease.
Lancet. 1985 Mar 2;1(8427):504-6. doi: 10.1016/s0140-6736(85)92097-5.
6
Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein.患羊瘙痒症的绵羊脑血管中的淀粉样蛋白与朊病毒蛋白抗体发生反应。
Neurosci Lett. 1988 Oct 5;92(2):234-9. doi: 10.1016/0304-3940(88)90067-5.
7
Amyloidogenesis in Alzheimer disease and scrapie.
Prog Clin Biol Res. 1989;317:869-76.
8
Recent developments in scrapie and Creutzfeldt-Jakob disease.
Prog Med Virol. 1986;33:78-98.
9
Amyloid scrapie plaques in mice, and Alzheimer senile plaques, share common antigens with tau, a microtubule-associated protein.
Neurosci Lett. 1987 Jul 9;78(1):113-8. doi: 10.1016/0304-3940(87)90571-4.
10
[Prion-type pathologies: from scrapie to prion-related dementias. On the borderline between veterinary and human pathology].
Rev Neurol. 1996 Jul;24(131):785-802.

引用本文的文献

1
A single-snapshot inverse solver for two-species graph model of tau pathology spreading in human Alzheimer's disease.用于人类阿尔茨海默病中tau病理传播的双物种图模型的单快照逆解算器
Brain Inform. 2025 Jul 9;12(1):18. doi: 10.1186/s40708-025-00264-z.
2
Alpha-synuclein seeding amplification assays in Lewy body dementia: a brief review.路易体痴呆中的α-突触核蛋白种子扩增检测：简要综述
Mol Neurodegener. 2025 Jul 1;20(1):77. doi: 10.1186/s13024-025-00868-3.
3
Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses.
追踪支架蛋白DISC1的聚集途径：对慢性精神疾病的结构影响
J Struct Biol X. 2025 May 24;11:100128. doi: 10.1016/j.yjsbx.2025.100128. eCollection 2025 Jun.
4
Modeling Protein Aggregation Kinetics from NMR Data.从核磁共振数据建模蛋白质聚集动力学。
J Mol Biol. 2025 Jun 9:169269. doi: 10.1016/j.jmb.2025.169269.
5
Overexpression in of an intrinsically disordered protein segment of UT impairs the parasite's proteostasis and reduces its growth rate.在UT中过表达一种内在无序的蛋白质片段会损害寄生虫的蛋白质稳态并降低其生长速率。
Front Cell Infect Microbiol. 2025 May 13;15:1565814. doi: 10.3389/fcimb.2025.1565814. eCollection 2025.
6
Doxycycline: An essential tool for Alzheimer's disease.强力霉素：治疗阿尔茨海默病的重要工具。
Biomed Pharmacother. 2025 Jul;188:118159. doi: 10.1016/j.biopha.2025.118159. Epub 2025 May 13.
7
Effect of hydrogen sulfide on alpha-synuclein aggregation and cell viability.硫化氢对α-突触核蛋白聚集及细胞活力的影响。
Sci Rep. 2025 May 4;15(1):15597. doi: 10.1038/s41598-025-99794-z.
8
On the reversibility of amyloid fibril formation.关于淀粉样纤维形成的可逆性
Biophys Rev (Melville). 2025 Jan 29;6(1):011303. doi: 10.1063/5.0236947. eCollection 2025 Mar.
9
Cathepsin B prevents cell death by fragmentation and destruction of pathological amyloid fibrils.组织蛋白酶B通过分解和破坏病理性淀粉样原纤维来防止细胞死亡。
Cell Death Discov. 2025 Feb 15;11(1):61. doi: 10.1038/s41420-025-02343-w.
10
ALZ-801 prevents amyloid β-protein assembly and reduces cytotoxicity: A preclinical experimental study.ALZ-801可预防β-淀粉样蛋白组装并降低细胞毒性：一项临床前实验研究。
FASEB J. 2025 Feb 15;39(3):e70382. doi: 10.1096/fj.202402622R.