Ascoli V, Albedi F M, De Blasiis R, Nardi F
Department of Biopathology, University La Sapienza, Rome, Italy.
Diagn Cytopathol. 1993;9(2):151-5. doi: 10.1002/dc.2840090208.
Four patients presented with a history of recurrent bilateral swellings of parotid glands. Fine-needle aspiration (FNA) specimens showed highly cellular smears containing clusters of enlarged acini and numerous naked nuclei. A diagnosis consistent with sialadenosis was made considering the distinct morphologic appearance: micrometric measurements in all cases, in addition to histology and electron microscopy in two cases confirmed this hypothesis. A review of clinical histories revealed hormonal, nutritional and neurogenic disorders, which are known to be associated with sialadenosis. In the work-up of salivary gland swellings, it is important to recognize cytologically this underestimated entity, which does not necessarily require surgical treatment.
4例患者有双侧腮腺反复肿胀病史。细针穿刺（FNA）标本显示涂片细胞丰富，含有扩大腺泡簇和大量裸核。考虑到独特的形态学表现，做出了符合涎腺肿大的诊断：所有病例均进行了微米测量，另外2例进行了组织学和电子显微镜检查以证实这一假设。回顾临床病史发现了已知与涎腺肿大相关的激素、营养和神经源性疾病。在唾液腺肿胀的检查中，从细胞学上识别这种被低估的疾病很重要，该病不一定需要手术治疗。
