Susani M, Madersbacher S, Kratzik C, Vingers L, Marberger M
Department of Clinical Pathology, University of Vienna, Austria.
Eur Urol. 1993;23 Suppl 1:34-8. doi: 10.1159/000474677.
The effect of high-intensity focused ultrasound (HIFU) ablation on the morphology of prostatic, renal and testicular tissue was studied by light and electron microscopy. Specimens were obtained in 21 patients 1 h to 10 weeks after lesioning. Histological findings showed consistent coagulative necrosis with precisely defined, sharp margins to normal tissue. Lesion size and position correlated well with the assumed target zones, suggesting that HIFU permits therapeutic tissue ablation.
通过光学显微镜和电子显微镜研究了高强度聚焦超声（HIFU）消融对前列腺、肾脏和睾丸组织形态的影响。在21例患者损伤后1小时至10周获取标本。组织学结果显示一致的凝固性坏死，与正常组织界限清晰、边缘锐利。病变大小和位置与假定的靶区相关性良好，表明HIFU可实现治疗性组织消融。
