Höhmann D, Waner M, Schwager K
Universitäts-HNO-Klinik Würzburg.
HNO. 1993 Apr;41(4):173-8.
Laser surgery techniques have become well established in otolaryngology. Yellow light lasers emit light in the visible spectrum. Laser light in the spectrum of 380-700 nm shows different effects after absorption at a specific chromophore. For the treatment of vascular lesions of the skin controlled absorption of energy by blood is necessary to avoid uncontrolled damage and vaporization. Chromophores of the skin which absorb energy transmitted by laser light are hemoglobin, bilirubin, oxyhemoglobin, beta carotene, collagen and melanin. The penetration of the laser light depends on its wavelength. In vascular lesions oxyhemoglobin is the chromophore whereas melanin is the chromophore in pigmented malformations. The argon-pumped dye laser, copper vapor and flash-lamp pumped dye laser emit laser light of 577, 578 and 585 nm. These lasers are especially useful for photocoagulation of oxyhemoglobin and for selective destruction of vascular tissue. The risk of hypotrophic or hypertrophic scarring is minimal (< 1%) because there is less alteration of the overlying dermis. The aim of the present study was to test, in a clinical setting, the copper vapor laser in vascular lesions of the head and neck.
激光手术技术在耳鼻喉科已得到广泛应用。黄光激光在可见光谱范围内发射光。380 - 700纳米光谱范围内的激光在特定发色团吸收后会表现出不同的效果。对于皮肤血管病变的治疗，需要血液对能量进行可控吸收，以避免不受控制的损伤和汽化。皮肤中吸收激光传输能量的发色团有血红蛋白、胆红素、氧合血红蛋白、β - 胡萝卜素、胶原蛋白和黑色素。激光的穿透取决于其波长。在血管病变中，氧合血红蛋白是发色团，而在色素性畸形中黑色素是发色团。氩泵浦染料激光、铜蒸气激光和闪光灯泵浦染料激光发射577、578和585纳米的激光。这些激光对于氧合血红蛋白的光凝和血管组织的选择性破坏特别有用。由于上层真皮的改变较小，出现萎缩性或肥厚性瘢痕的风险极小（<1%）。本研究的目的是在临床环境中测试铜蒸气激光对头颈部血管病变的治疗效果。
