de Maddalena H, Pfrang H
Abteilung für Phoniatrie und Pädaudiologie, Universitäts-Hals-Nasen-Ohren-Klinik Tübingen.
HNO. 1993 Apr;41(4):198-205.
One or two days before operation 62 male patients with laryngeal or pharyngeal malignancies were questioned about their subjective beliefs concerning the causes of their cancer. Additionally they were asked about their current and past tobacco and alcohol consumption. Six months after the operation 51 of the 62 patients were interviewed about their psychosocial adjustment and their postoperative tobacco and alcohol consumption. Before the operation most of the patients (81%) reported that they already had been thinking about the possible causes of their malignant disease. Four out of five patients were smokers and consumed alcohol daily, at least until disease onset. According to psychiatric criteria more than 50% of the daily alcohol consumers were diagnosed as alcoholics. As was expected, "smoking" was rated as the most important causal factor in tumor etiology. Furthermore, "air pollution", "unhealthy working conditions" and "fate" were rated as important pathogenic factors of the individual cancer. Surprisingly "alcohol" was only rated as an important causal factor by a few patients. The causal factor "smoking" was correlated neither with actual pre- and postoperative smoking behavior, nor with postoperative psychosocial adjustment. "Alcohol" was positively associated with a postoperative reduction of alcohol consumption, on the one hand, and with increased postoperative psychological distress, on the other. Significant positive relationships were also found between "fate" and postoperative psychological distress and rejection of altered voice (e.g. laryngectomy). In conclusion, medical information about the possible causes of cancer should try to focus the attention of the patients on current and future stress factors and not on past risk behavior (e.g. alcohol and tobacco consumption), which cannot be altered retrospectively.(ABSTRACT TRUNCATED AT 250 WORDS)
在手术前一至两天,对62名患有喉癌或咽癌的男性患者询问了他们对癌症病因的主观看法。此外,还询问了他们当前及过去的烟酒消费情况。手术后六个月,对62名患者中的51名进行了访谈,了解他们的心理社会适应情况以及术后的烟酒消费情况。手术前,大多数患者(81%)表示他们已经在思考自己患恶性疾病的可能原因。五分之四的患者吸烟且每天饮酒,至少直到疾病发作。根据精神病学标准,超过50%的每日饮酒者被诊断为酗酒者。正如预期的那样,“吸烟”被认为是肿瘤病因中最重要的致病因素。此外,“空气污染”“不健康的工作条件”和“命运”被认为是个体癌症的重要致病因素。令人惊讶的是,只有少数患者将“酒精”视为重要的致病因素。致病因素“吸烟”与术前及术后的实际吸烟行为均无关联,也与术后的心理社会适应情况无关。“酒精”一方面与术后酒精消费量的减少呈正相关,另一方面与术后心理困扰的增加呈正相关。“命运”与术后心理困扰以及对嗓音改变(如喉切除术)的排斥之间也发现了显著的正相关关系。总之,关于癌症可能病因的医学信息应将患者的注意力集中在当前和未来的压力因素上,而不是过去无法追溯改变的风险行为(如烟酒消费)上。(摘要截选至250词)