Zimmermann M, Schorcht J, Andree W
Research Institute M. v. Ardenne, Dresden, Germany.
Int J Hyperthermia. 1993 May-Jun;9(3):463-77. doi: 10.3109/02656739309005045.
This paper describes a new type of applicator system for the intracavitary radiothermotherapy of gynaecological tumours. Hyperthermia and radiation can be delivered by one and the same applicator. The hyperthermia is delivered by a modified capacitive heating technique (27.12 MHz) combined with cooling systems, the radiation by the numerically controlled oscillation of a gamma source on the inside of the main applicator, the RF gamma applicator (HDR afterloading technique). Isotherms and isodoses can be adapted to the anatomical-pathological situation. Interactions between the applicator system and the surrounding tissue were investigated in a theoretical model (FEM). Complex two-dimensional SAR calculations as well as three-dimensional temperature calculations were carried out. The RF gamma applicator was also examined by thermography; the thermography proved the theoretical modelling to be correct. The applicators were also tested in animal experiments.
本文介绍了一种用于妇科肿瘤腔内放射热疗的新型施源器系统。热疗和放疗可通过同一个施源器进行。热疗采用改进的电容加热技术（27.12兆赫兹）并结合冷却系统来实现，放疗则通过主施源器内部伽马源的数控振荡来实现，即射频伽马施源器（高剂量率后装技术）。等温线和等剂量线可根据解剖病理情况进行调整。在一个理论模型（有限元法）中研究了施源器系统与周围组织之间的相互作用。进行了复杂的二维比吸收率计算以及三维温度计算。还通过热成像对射频伽马施源器进行了检测；热成像证明理论建模是正确的。这些施源器也在动物实验中进行了测试。
