Avis S P, Hutton C J
Memorial University of Newfoundland, Health Science Centre, St. John's, Canada.
J Forensic Sci. 1993 May;38(3):599-602.
The toxicity of benzene is well established, particularly its chronic effects on the hematopoietic system and its role as a carcinogen. Acute effects are known but less well documented. This case report describes three cases of acute benzene poisoning resulting from an industrial accident aboard a chemical cargo ship. Complete autopsies were performed on all three victims, who showed evidence of cutaneous, respiratory and cerebral injury. In addition, body fluids, brain, body fat, liver and lung were analyzed for benzene, levels of which were consistent with the lipid soluble nature of benzene, although body fat showed better correlation with blood levels than brain, liver or bile.
苯的毒性已得到充分证实，尤其是其对造血系统的慢性影响以及作为致癌物的作用。急性影响是已知的，但记录较少。本病例报告描述了一起化学品货船上工业事故导致的三例急性苯中毒病例。对所有三名受害者进行了完整的尸检，结果显示有皮肤、呼吸和脑部损伤的证据。此外，还对体液、大脑、体脂、肝脏和肺部进行了苯分析，其含量与苯的脂溶性相符，尽管体脂与血液水平的相关性比大脑、肝脏或胆汁更好。
