Twickler D, Budorick N, Pretorius D, Grafe M, Currarino G
Department of Radiology, University of Texas Southwestern Medical School, Dallas 75235-7786.
J Ultrasound Med. 1993 Jun;12(6):323-30. doi: 10.7863/jum.1993.12.6.323.
Seven cases with the pathologic/autopsy diagnosis of caudal regression or sirenomelia in which antenatal sonography had been performed were reviewed. The three patients with caudal regression had similar findings on antenatal sonogram, including normal or increased amniotic fluid, mild dilation or normal urinary systems, nonfused extremities, and sacral agenesis. In the four patients with sirenomelia, common sonographic findings included marked oligohydramnios, suspected renal agenesis, and sacral agenesis. A history of maternal diabetes was elicited in all patients with caudal regression and in none of the patients with sirenomelia. Findings confirm recent articles in pediatric pathology suggesting that caudal regression is a separate entity, distinct from sirenomelia.
回顾了7例经病理/尸检诊断为尾椎退化综合征或并腿畸形且产前已行超声检查的病例。3例尾椎退化综合征患者的产前超声检查结果相似，包括羊水正常或增多、泌尿系统轻度扩张或正常、肢体未融合以及骶骨发育不全。4例并腿畸形患者的常见超声检查结果包括羊水过少、疑似肾缺如和骶骨发育不全。所有尾椎退化综合征患者均有母亲糖尿病史，而并腿畸形患者均无此病史。这些发现证实了儿科病理学领域近期的文章观点，即尾椎退化综合征是一个独立的实体，与并腿畸形不同。
