Shinzato T, Uema H, Inadome J, Shimoji K, Kusano N, Fukuhara H, Saito A, Taira M, Nakamura H
First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1993 Apr;31(4):486-91.
The bacteriology of empyema fluid and the clinical background of 23 cases from July 1987 through July 1992 were studied. Nineteen cases were male and 4 female, with a mean age of 59.6 years (range; 33 to 84 y.o.). There were 15 cases of community-acquired infection and 8 of nosocomial infection. Acute pneumonia and/or lung abscess developed into empyema in 19 cases. Sixteen cases had associated predisposing conditions, such as diabetes, chronic bronchitis, disorders with dysphagia, and excess alcohol intake. Forty-one strains were isolated from empyema in 22 cases. The predominant organisms, in order of prevalence, were "Streptococcus milleri" group (11 strains), Peptostreptococcus spp. (6), Prevotella spp. (6), Fusobacterium spp. (5) and other viridans streptococci (3). The majority of streptococcal infections, which were primarily caused by "S. milleri" group, were mixed with anaerobes and/or aerobes/facultatives. These results demonstrate that oral streptococci, especially "S. milleri" group, and anaerobes play a significant role as pathogens in empyema.
对1987年7月至1992年7月期间23例脓胸患者胸腔积液的细菌学及临床背景进行了研究。其中男性19例，女性4例，平均年龄59.6岁（范围：33至84岁）。社区获得性感染15例，医院获得性感染8例。19例由急性肺炎和/或肺脓肿发展为脓胸。16例伴有易感因素，如糖尿病、慢性支气管炎、吞咽困难疾病及过量饮酒。22例脓胸患者中共分离出41株菌株。按流行率排序，主要病原菌为米勒链球菌群（11株）、消化链球菌属（6株）、普雷沃菌属（6株）、梭杆菌属（5株）及其他草绿色链球菌（3株）。大多数链球菌感染主要由米勒链球菌群引起，且与厌氧菌和/或需氧菌/兼性菌混合感染。这些结果表明，口腔链球菌，尤其是米勒链球菌群和厌氧菌在脓胸病原菌中起重要作用。
