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[Several kinetic features of membrane-dependent monoamine oxidase].

作者信息

Vasil'evykh L G, Gorkin V Z, Kagan Z S

出版信息

Biull Eksp Biol Med. 1977 Mar;83(3):288-9.

PMID:851631
Abstract

The v versus (S) plots for the initial rates of serotonin oxidation, catalyzed by monoamine oxidase in fragments of the rat liver or bovine brain mitochondrial membrane, had complicated non-hyperbolic shape, suggesting kinetic manifestation of cooperation in binding the substrate by the enzyme. A possibility of interactions of different monoamine oxidase types via the conformational alterations in the bio-membrane itself is considered.

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